PhD thesis supervisor: dr. Artūras Ulčinas (apply for recommendation)
Fast-scanning wide-field atomic force microscopy for high-throughput nanoscale characterization of biological and biomimetic materials
High-resolution microscopy has transformed how we study biological materials, revealing how their complex nanoscale structure determines function and behavior. However, most high-resolution techniques still suffer from practical limitations—such as low throughput, small fields of view, or demanding sample preparation—that restrict their use in large-scale studies. Atomic force microscopy (AFM), for example, is one of the most powerful tools for nanoscale imaging and mechanical characterization, yet traditional systems are limited by slow scanning speeds.
In this PhD project, the researcher will seek to advance innovative methods that leverage a state-of-the-art fast-scanning, large-field-of-view AFM developed at FTMC. This technology will be applied to study biological structures and processes across multiple length scales—for example, the nanoscale ultrastructure of mineralized tissues such as tooth enamel, or the internalization of microplastics in cells. This work will contribute to bridging the gap between nanoscale observations and macroscale biological phenomena, helping to uncover new knowledge about physical principles underlying biological matter.
The project will be carried out in a highly interdisciplinary research environment, collaborating closely with experts in physics, electronics, chemistry, and biology. This setting offers excellent opportunities for scientific growth, hands-on experience with advanced instrumentation, and meaningful contributions to cutting-edge biophysical research.